Product Name: GMCL1L Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: ALEXA FLUOR® 647
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human GMCL1L
Clonality: Polyclonal
CAS NO: 2508-72-7
Product: Endoxifen (E-isomer hydrochloride)
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: GCL; Germ cell less homolog 1 Drosophila like; Germ cell less protein like 1 like; GMCL 2; GMCL2; GMCLL_HUMAN.
Background: GMCL1L has a possible function in spermatogenesis. It enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport. GMCL1L is also a probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23811932?dopt=Abstract
