Product Name: GNAI3 Polyclonal Antibody, Cy3 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: Cy3
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human GNAI3
Clonality: Polyclonal
CAS NO: 1263-89-4
Product: RRx-001
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: GAI3; 87U6; FLJ26559; G protein alpha inhibiting 3; Gi alpha 3; Gi alpha-3; GNAI3; GNAI3_HUMAN; Guanine nucleotide binding protein G protein alpha inhibiting activity polypeptide 3; Guanine nucleotide binding protein Gk alpha subunit; Guanine nucleotide-binding protein Gk subunit alpha; OTTHUMP00000013368; Gnai3; Guanine nucleotide binding protein G protein, alpha inhibiting 3; G Alpha i-3.
Background: GAI3 is the a subunit of inhibitory trimeric G protein (Gi), which inhibits adenylate cyclase once its G protein coupled receptors (GPCR) such as a2 adrenergic receptors are activated. GAI3 can be inactivated by pertussis toxin. Guanine nucleotide binding proteins are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor regulated K(+) channels.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24835245?dopt=Abstract
