Product Name: GOLGA6 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated
Applications: IF(IHC-P)
Reactivity: Human
Conjugation: ALEXA FLUOR® 647
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human GOLGA6
Clonality: Polyclonal
CAS NO: 85700-55-6
Product: Aprotinin
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: GLP; GOG6A_HUMAN; GOLGA; GOLGA6; GOLGA6A; Golgi autoantigen golgin subfamily a 6; golgi autoantigen golgin subfamily a member 6; golgin like protein; Golgin linked to PML; Golgin subfamily A member 6A; Golgin-like protein; HGNC:13567.
Background: The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The protein encoded by this gene is a member of the golgin family of proteins, whose members localize to the Golgi. This gene is found in a large, low copy repeat sequence or duplicon that is found in multiple copies, that are greather than 90% similar, on chromosome 15. Duplicons are associated with deletions, inversions and other chromosome rearrangements that underlie genomic disease. The protein encoded by this gene is thought to be a functional golgin protein while the majority of the related copies of this gene are thought to be transcribed pseudogenes.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19966310?dopt=Abstract
