Product Name: GPCR EX33 Polyclonal Antibody
Applications: WB, FCM, IHC-P, IF(IHC-P)
Reactivity: Human, Mouse
Conjugation: Unconjugated
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human GPCR EX33 protein
Clonality: Polyclonal
CAS NO: 1253186-49-0
Product: Carsalam
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Synonyms: EX33; GPCR4; G-protein coupled receptor 84; Inflammation-related G-protein coupled receptor EX33; GPR84
Background: Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26714639?dopt=Abstract
