Product Name: GPR110 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated
Applications: FCM, IF(IHC-P)
Reactivity: Human, Mouse
Conjugation: ALEXA FLUOR® 555
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human G protein coupled receptor 110
Clonality: Polyclonal
CAS NO: 828934-41-4
Product: SB 242084
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: PGR19; GPR110; KPG_012; hGPCR36; Adhesion G-protein coupled receptor F1; G-protein coupled receptor 110; G-protein coupled receptor KPG_012; G-protein coupled receptor PGR19; ADGRF1
Background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR110 (G protein-coupled receptor 110), also known as PGR19, is a 911 amino acid protein that belongs to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Characterized as an adhesion GPCR, GPR110 is a multipass membrane-bound protein with a long amino-terminus that contains multiple domains. One of these domains is the GPCR proteolytic site (GPS), which is essential for proteolytic cleavage of the amino-terminus and for cell surface expression.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25423885?dopt=Abstract
