Product Name: Glycodelin A/PP14 Polyclonal Antibody, Cy7 Conjugated
Applications: IF(IHC-P)
Reactivity: Human
Conjugation: Cy7
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human Glycodelin A/PP14
Clonality: Polyclonal
CAS NO: 900305-37-5
Product: alpha-Hederin
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: alpha uterine protein; GD; GdA; GdF; GdS; Glycodelin; Glycodelin F; Glycodelin S; PAEG; PAEP; PAEP protein; PEG; PEP; PP14; Pregnancy associated endometrial alpha 2 globulin; Progestagen associated endometrial protein placental protein 14; Progestagen associated endometrial protein; Progesterone associated endometrial protein; MGC138509; MGC142288.
Background: This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined. [provided by RefSeq].
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/12930829?dopt=Abstract
