Product Name :
PC Biotin-PEG3-alkyne
Description:
PC Biotin-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CAS:
1869922-24-6
Molecular Weight:
780.89
Formula:
C35H52N6O12S
Chemical Name:
1-(4-{3-[(2-{2-[2-(2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}ethoxy)ethoxy]ethoxy}ethyl)carbamoyl]propoxy}-5-methoxy-2-nitrophenyl)ethyl N-(prop-2-yn-1-yl)carbamate
Smiles :
CC(OC(=O)NCC#C)C1=CC(OC)=C(C=C1[N+]([O-])=O)OCCCC(=O)NCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
InChiKey:
HRHZIAGPIYYJMG-MJUSKHNJSA-N
InChi :
InChI=1S/C35H52N6O12S/c1-4-11-38-35(45)53-24(2)25-21-28(48-3)29(22-27(25)41(46)47)52-14-7-10-32(43)37-13-16-50-18-20-51-19-17-49-15-12-36-31(42)9-6-5-8-30-33-26(23-54-30)39-34(44)40-33/h1,21-22,24,26,30,33H,5-20,23H2,2-3H3,(H,36,42)(H,37,43)(H,38,45)(H2,39,40,44)/t24?,26-,30-,33-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ocrelizumab} site|{Ocrelizumab} CD20|{Ocrelizumab} Technical Information|{Ocrelizumab} In stock|{Ocrelizumab} supplier|{Ocrelizumab} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Lonigutamab} site|{Lonigutamab} Antibody-drug Conjugate/ADC Related|{Lonigutamab} Protocol|{Lonigutamab} Data Sheet|{Lonigutamab} supplier|{Lonigutamab} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24013184
Additional information:
PC Biotin-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).|Product information|CAS Number: 1869922-24-6|Molecular Weight: 780.89|Formula: C35H52N6O12S|Chemical Name: 1-(4-{3-[(2-{2-[2-(2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}ethoxy)ethoxy]ethoxy}ethyl)carbamoyl]propoxy}-5-methoxy-2-nitrophenyl)ethyl N-(prop-2-yn-1-yl)carbamate|Smiles: CC(OC(=O)NCC#C)C1=CC(OC)=C(C=C1[N+]([O-])=O)OCCCC(=O)NCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12|InChiKey: HRHZIAGPIYYJMG-MJUSKHNJSA-N|InChi: InChI=1S/C35H52N6O12S/c1-4-11-38-35(45)53-24(2)25-21-28(48-3)29(22-27(25)41(46)47)52-14-7-10-32(43)37-13-16-50-18-20-51-19-17-49-15-12-36-31(42)9-6-5-8-30-33-26(23-54-30)39-34(44)40-33/h1,21-22,24,26,30,33H,5-20,23H2,2-3H3,(H,36,42)(H,37,43)(H,38,45)(H2,39,40,44)/t24?,26-,30-,33-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.|Products are for research use only. Not for human use.|
