Product Name :
MK-2894 Sodium Salt
Description:
MK-2894 is a potent and selective prostaglandin E2 subtype 4 receptor (PGE2) antagonist. MK-2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin.
CAS:
1006036-88-9
Molecular Weight:
495.49
Formula:
C25H21F3NNaO3S
Chemical Name:
sodium 4-[1-(2,5-dimethyl-4-{[4-(trifluoromethyl)phenyl]methyl}thiophene-3-amido)cyclopropyl]benzoate
Smiles :
[Na+].CC1SC(C)=C(C=1CC1C=CC(=CC=1)C(F)(F)F)C(=O)NC1(CC1)C1C=CC(=CC=1)C([O-])=O
InChiKey:
RQRUUNKVGDVBFV-UHFFFAOYSA-M
InChi :
InChI=1S/C25H22F3NO3S.Na/c1-14-20(13-16-3-7-19(8-4-16)25(26,27)28)21(15(2)33-14)22(30)29-24(11-12-24)18-9-5-17(6-10-18)23(31)32;/h3-10H,11-13H2,1-2H3,(H,29,30)(H,31,32);/q;+1/p-1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Neuromedin B} MedChemExpress|{Neuromedin B} Metabolic Enzyme/Protease|{Neuromedin B} Protocol|{Neuromedin B} Formula|{Neuromedin B} supplier|{Neuromedin B} Cancer}
Shelf Life:
≥360 days if stored properly.{{Cefiderocol} medchemexpress|{Cefiderocol} Antibiotic|{Cefiderocol} Biological Activity|{Cefiderocol} References|{Cefiderocol} manufacturer|{Cefiderocol} Cancer}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23773119
Additional information:
MK-2894 is a potent and selective prostaglandin E2 subtype 4 receptor (PGE2) antagonist. MK-2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin.|Product information|CAS Number: 1006036-88-9|Molecular Weight: 495.49|Formula: C25H21F3NNaO3S|Chemical Name: sodium 4-[1-(2,5-dimethyl-4-{[4-(trifluoromethyl)phenyl]methyl}thiophene-3-amido)cyclopropyl]benzoate|Smiles: [Na+].CC1SC(C)=C(C=1CC1C=CC(=CC=1)C(F)(F)F)C(=O)NC1(CC1)C1C=CC(=CC=1)C([O-])=O|InChiKey: RQRUUNKVGDVBFV-UHFFFAOYSA-M|InChi: InChI=1S/C25H22F3NO3S.Na/c1-14-20(13-16-3-7-19(8-4-16)25(26,27)28)21(15(2)33-14)22(30)29-24(11-12-24)18-9-5-17(6-10-18)23(31)32;/h3-10H,11-13H2,1-2H3,(H,29,30)(H,31,32);/q;+1/p-1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
