Product Name :
PNZ5
Description:
PNZ5 is a potent and isoxazole-based pan-BET inhibitor with high selectivity and potency similar to the well-established (+)-JQ1, with a KD of 5.43 nM for BRD4(1).
CAS:
1629277-36-6
Molecular Weight:
318.37
Formula:
C20H18N2O2
Chemical Name:
(3S)-5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-methyl-3-phenyl-2,3-dihydro-1H-isoindol-1-one
Smiles :
CC1ON=C(C)C=1C1=CC2[C@H](C3C=CC=CC=3)N(C)C(=O)C=2C=C1
InChiKey:
CHAKVDDAHQGTLR-IBGZPJMESA-N
InChi :
InChI=1S/C20H18N2O2/c1-12-18(13(2)24-21-12)15-9-10-16-17(11-15)19(22(3)20(16)23)14-7-5-4-6-8-14/h4-11,19H,1-3H3/t19-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Pralatrexate} MedChemExpress|{Pralatrexate} Apoptosis|{Pralatrexate} Protocol|{Pralatrexate} In Vitro|{Pralatrexate} manufacturer|{Pralatrexate} Cancer}
Shelf Life:
≥12 months if stored properly.{{Talquetamab} site|{Talquetamab} Immunology/Inflammation|{Talquetamab} Purity & Documentation|{Talquetamab} Data Sheet|{Talquetamab} custom synthesis|{Talquetamab} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PNZ5 is a potent and isoxazole-based pan-BET inhibitor with high selectivity and potency similar to the well-established (+)-JQ1, with a KD of 5.43 nM for BRD4(1).|Product information|CAS Number: 1629277-36-6|Molecular Weight: 318.37|Formula: C20H18N2O2|Chemical Name: (3S)-5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-methyl-3-phenyl-2,3-dihydro-1H-isoindol-1-one|Smiles: CC1ON=C(C)C=1C1=CC2[C@H](C3C=CC=CC=3)N(C)C(=O)C=2C=C1|InChiKey: CHAKVDDAHQGTLR-IBGZPJMESA-N|InChi: InChI=1S/C20H18N2O2/c1-12-18(13(2)24-21-12)15-9-10-16-17(11-15)19(22(3)20(16)23)14-7-5-4-6-8-14/h4-11,19H,1-3H3/t19-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:27108903 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
