Product Name :
Nimbolide
Description:
Nimbolide is a natural inhibitor of pancreatic cancer growth and metastasis through ROS-mediated apoptosis. It inhibits epithelial-to-mesenchymal transition.
CAS:
25990-37-8
Molecular Weight:
466.52
Formula:
C27H30O7
Chemical Name:
8(R)-(3-Furanyl)-2aR, 5aR, 6S, 6aR, 8R, 9, 9aR, 10aS, 10bR, 10cR-decahydro-2a, 5a, 6a, 7-tetramethyl-2, 5-dioxo-2H, 5H-cyclopenta[d’]naphtho[1, 8-bc:2, 3-b’]difuran-6-acetic acid, methyl ester
Smiles :
CC1[C@@H](C[C@H]2O[C@@H]3[C@@H]4OC(=O)[C@]5(C)C=CC(=O)[C@@](C)([C@H]54)[C@@H](CC(=O)OC)[C@]3(C)C=12)C1=COC=C1
InChiKey:
JZIQWNPPBKFOPT-LSYMHUITSA-N
InChi :
InChI=1S/C27H30O7/c1-13-15(14-7-9-32-12-14)10-16-20(13)27(4)17(11-19(29)31-5)26(3)18(28)6-8-25(2)22(26)21(23(27)33-16)34-24(25)30/h6-9,12,15-17,21-23H,10-11H2,1-5H3/t15-,16-,17-,21-,22+,23-,25-,26+,27-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Nitro blue tetrazolium} medchemexpress|{Nitro blue tetrazolium} {Fluorescent Dye}|{Nitro blue tetrazolium} Purity & Documentation|{Nitro blue tetrazolium} Formula|{Nitro blue tetrazolium} manufacturer|{Nitro blue tetrazolium} Autophagy}
Shelf Life:
≥12 months if stored properly.{{Mifepristone} medchemexpress|{Mifepristone} Immunology/Inflammation|{Mifepristone} Technical Information|{Mifepristone} Formula|{Mifepristone} manufacturer|{Mifepristone} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23833812
Additional information:
Nimbolide is a natural inhibitor of pancreatic cancer growth and metastasis through ROS-mediated apoptosis. It inhibits epithelial-to-mesenchymal transition.|Product information|CAS Number: 25990-37-8|Molecular Weight: 466.52|Formula: C27H30O7|Chemical Name: 8(R)-(3-Furanyl)-2aR, 5aR, 6S, 6aR, 8R, 9, 9aR, 10aS, 10bR, 10cR-decahydro-2a, 5a, 6a, 7-tetramethyl-2, 5-dioxo-2H, 5H-cyclopenta[d’]naphtho[1, 8-bc:2, 3-b’]difuran-6-acetic acid, methyl ester|Smiles: CC1[C@@H](C[C@H]2O[C@@H]3[C@@H]4OC(=O)[C@]5(C)C=CC(=O)[C@@](C)([C@H]54)[C@@H](CC(=O)OC)[C@]3(C)C=12)C1=COC=C1|InChiKey: JZIQWNPPBKFOPT-LSYMHUITSA-N|InChi: InChI=1S/C27H30O7/c1-13-15(14-7-9-32-12-14)10-16-20(13)27(4)17(11-19(29)31-5)26(3)18(28)6-8-25(2)22(26)21(23(27)33-16)34-24(25)30/h6-9,12,15-17,21-23H,10-11H2,1-5H3/t15-,16-,17-,21-,22+,23-,25-,26+,27-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Bodduluru LN, et al. Chemopreventive and therapeutic effects of nimbolide in cancer: the underlying mechanisms. Toxicol In Vitro. 2014 Aug;28(5):1026-35.Products are for research use only. Not for human use.|
