Product Name :
KDM4D-IN-1
Description:
KDM4D-IN-1 is a new histone lysine demethylase 4D (KDM4D) inhibitor with an IC50 value of 0.41±0.03 μM.
CAS:
2098902-68-0
Molecular Weight:
225.21
Formula:
C11H7N5O
Chemical Name:
8-hydroxy-4-methyl-2,3,7,13-tetraazatricyclo[7.4.0.0²,⁶]trideca-1(13),3,5,7,9,11-hexaene-5-carbonitrile
Smiles :
CC1=NN2C3=NC=CC=C3C(O)=NC2=C1C#N
InChiKey:
FIRSAIIBSBCBTF-UHFFFAOYSA-N
InChi :
InChI=1S/C11H7N5O/c1-6-8(5-12)10-14-11(17)7-3-2-4-13-9(7)16(10)15-6/h2-4H,1H3,(H,14,17)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
KDM4D-IN-1 is a new histone lysine demethylase 4D (KDM4D) inhibitor with an IC50 value of 0.41±0.03 μM.|Product information|CAS Number: 2098902-68-0|Molecular Weight: 225.21|Formula: C11H7N5O|Chemical Name: 8-hydroxy-4-methyl-2,3,7,13-tetraazatricyclo[7.4.0.0²,⁶]trideca-1(13),3,5,7,9,11-hexaene-5-carbonitrile|Smiles: CC1=NN2C3=NC=CC=C3C(O)=NC2=C1C#N|InChiKey: FIRSAIIBSBCBTF-UHFFFAOYSA-N|InChi: InChI=1S/C11H7N5O/c1-6-8(5-12)10-14-11(17)7-3-2-4-13-9(7)16(10)15-6/h2-4H,1H3,(H,14,17)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 7.{{Vasopressin} web|{Vasopressin} Metabolic Enzyme/Protease|{Vasopressin} Purity & Documentation|{Vasopressin} Formula|{Vasopressin} custom synthesis|{Vasopressin} Cancer} 14 mg/mL (31.{{Creatinine} MedChemExpress|{Creatinine} Metabolic Enzyme/Protease|{Creatinine} Technical Information|{Creatinine} Data Sheet|{Creatinine} custom synthesis|{Creatinine} Epigenetic Reader Domain} 70 mM; Need ultrasonic).PMID:23912708 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|KDM4D-IN-1 (Compound 10r) is the most potent one with an IC50 value of 0.41±0.03 μM against KDM4D. KDM4D-IN-1 displays almost no activity against KDM2B, KDM3B, and KDM5A (IC50>10 μM), indicating that KDM4D-IN-1 has a good selectivity for KDM4D against other selected KDMs.|Products are for research use only. Not for human use.|
