Product Name :
Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP
Description:
Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CAS:
253863-34-2
Molecular Weight:
802.83
Formula:
C40H46N6O12
Chemical Name:
{4-[(2S)-N-[(1S)-1-carbamoyl-5-{[(prop-2-en-1-yloxy)carbonyl]amino}pentyl]-3-phenyl-2-[(2R)-2-{[(prop-2-en-1-yloxy)carbonyl]amino}propanamido]propanamido]phenyl}methyl 4-nitrophenyl carbonate
Smiles :
C[C@@H](NC(=O)OCC=C)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N([C@@H](CCCCNC(=O)OCC=C)C(N)=O)C1=CC=C(COC(=O)OC2=CC=C(C=C2)[N+]([O-])=O)C=C1
InChiKey:
AZOIYVUEQXFWAV-KUSJRIKGSA-N
InChi :
InChI=1S/C40H46N6O12/c1-4-23-55-38(50)42-22-10-9-13-34(35(41)47)45(30-16-14-29(15-17-30)26-57-40(52)58-32-20-18-31(19-21-32)46(53)54)37(49)33(25-28-11-7-6-8-12-28)44-36(48)27(3)43-39(51)56-24-5-2/h4-8,11-12,14-21,27,33-34H,1-2,9-10,13,22-26H2,3H3,(H2,41,47)(H,42,50)(H,43,51)(H,44,48)/t27-,33+,34+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).|Product information|CAS Number: 253863-34-2|Molecular Weight: 802.83|Formula: C40H46N6O12|Chemical Name: {4-[(2S)-N-[(1S)-1-carbamoyl-5-{[(prop-2-en-1-yloxy)carbonyl]amino}pentyl]-3-phenyl-2-[(2R)-2-{[(prop-2-en-1-yloxy)carbonyl]amino}propanamido]propanamido]phenyl}methyl 4-nitrophenyl carbonate|Smiles: C[C@@H](NC(=O)OCC=C)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N([C@@H](CCCCNC(=O)OCC=C)C(N)=O)C1=CC=C(COC(=O)OC2=CC=C(C=C2)[N+]([O-])=O)C=C1|InChiKey: AZOIYVUEQXFWAV-KUSJRIKGSA-N|InChi: InChI=1S/C40H46N6O12/c1-4-23-55-38(50)42-22-10-9-13-34(35(41)47)45(30-16-14-29(15-17-30)26-57-40(52)58-32-20-18-31(19-21-32)46(53)54)37(49)33(25-28-11-7-6-8-12-28)44-36(48)27(3)43-39(51)56-24-5-2/h4-8,11-12,14-21,27,33-34H,1-2,9-10,13,22-26H2,3H3,(H2,41,47)(H,42,50)(H,43,51)(H,44,48)/t27-,33+,34+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Lapatinib} site|{Lapatinib} EGFR|{Lapatinib} Technical Information|{Lapatinib} In Vitro|{Lapatinib} supplier|{Lapatinib} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Mitapivat} web|{Mitapivat} Pyruvate Kinase|{Mitapivat} Biological Activity|{Mitapivat} Purity|{Mitapivat} supplier|{Mitapivat} Epigenetics} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33050761 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
