Product Name :
Human Ephrin Type A receptor 2 Recombinant monoclonal antibody (1C1) (Rabbit IgGκ)
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Stable at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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| Alternative Name EphA2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK | Application ELISA, Flow Cytometry, IF, WB | Clone 1C1 | Formulation Liquid. In PBS containing 0.02% Proclin 300. | Host Rabbit | Immunogen 1C1 was isolated after screening of a non-immunized human Fab phage library. Selection was based on the ability to bind soluble human recombinant EphA2 (residues 183-510). The Fab was subsequently converted to full length human IgG1. | Isotype IgGκ | Species Reactivity Human | Specificity Recognizes the N-termianal LBD (ligand-binding domain) region of the EphA2 ectodomain (IgG1 KD ~0.{{2734858-36-5} web|{2734858-36-5} Technical Information|{2734858-36-5} In stock|{2734858-36-5} manufacturer} 8 nM; Fab KD ~140 nM) and not to other related human Eph receptors such as EphA1, EphA2, and EphA4, or any EphB receptor family members.{{2928571-43-9} web|{2928571-43-9} Protocol|{2928571-43-9} Purity|{2928571-43-9} custom synthesis} | Technical Info / Product Notes This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.PMID:30725635 | UniProt ID P29317 | Unit of Measure (UM) µg
