Product Name :
Radicicol
Description:
Radicicol is an inhibitor of Hsp90 with an IC50 value of 1 μM. Radicicol binds to the ATPase domain of Hsp90 and prevents maturation of Hsp90 clients, leading to proteasomal degradation. Radicicol is an antifungal antibiotic with antimalarial activity, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB.
CAS:
12772-57-5
Molecular Weight:
364.78
Formula:
C18H17ClO6
Chemical Name:
16-chloro-17,19-dihydroxy-4-methyl-3,7-dioxatricyclo[13.4.0.Docosahexaenoic Acid Metabolic Enzyme/Protease 0⁶,⁸]nonadeca-1(15),9,11,16,18-pentaene-2,13-dione
Smiles :
CC1CC2OC2C=CC=CC(=O)CC2C(Cl)=C(O)C=C(O)C=2C(=O)O1
InChiKey:
WYZWZEOGROVVHK-JVLMNHKTSA-N
InChi :
InChI=1S/C18H17ClO6/c1-9-6-15-14(25-15)5-3-2-4-10(20)7-11-16(18(23)24-9)12(21)8-13(22)17(11)19/h2-5,8-9,14-15,21-22H,6-7H2,1H3/b4-2-,5-3-
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Nitisinone HPPD
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33250601
Additional information:
Radicicol is an inhibitor of Hsp90 with an IC50 value of 1 μM. Radicicol binds to the ATPase domain of Hsp90 and prevents maturation of Hsp90 clients, leading to proteasomal degradation. Radicicol is an antifungal antibiotic with antimalarial activity, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB.|Product information|CAS Number: 12772-57-5|Molecular Weight: 364.78|Formula: C18H17ClO6|Chemical Name: 16-chloro-17,19-dihydroxy-4-methyl-3,7-dioxatricyclo[13.4.0.0⁶,⁸]nonadeca-1(15),9,11,16,18-pentaene-2,13-dione|Smiles: CC1CC2OC2C=CC=CC(=O)CC2C(Cl)=C(O)C=C(O)C=2C(=O)O1|InChiKey: WYZWZEOGROVVHK-JVLMNHKTSA-N|InChi: InChI=1S/C18H17ClO6/c1-9-6-15-14(25-15)5-3-2-4-10(20)7-11-16(18(23)24-9)12(21)8-13(22)17(11)19/h2-5,8-9,14-15,21-22H,6-7H2,1H3/b4-2-,5-3-|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
