Product Name :
2-Iodoacetamide, 98%, stab. with ca 5-8% water
Synonym:
IUPAC Name :
2-iodoacetamide
CAS NO.:
144-48-9
Molecular Weight :
Molecular formula:
C2H4INO
Smiles:
NC(=O)CI
Description:
Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine.Flucytosine It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds.EN4 It is involved as an inhibitor of deubiquitinase enzymes (DUBs).PMID:23557924 Further, it acts as an alkylating sulfhydryl reagent.
