Product Name :
INNO-206
Description:
Aldoxorubicin, also known as INNO-206 and Doxorubicin-EMCH, is a prodrug of the anthracycline antibiotic doxorubicin. Aldoxorubicin binds selectively to the cysteine-34 position of albumin via its maleimide moiety, inhibiting DNA synthesis and inducing apoptosis.
CAS:
1361644-26-9
Molecular Weight:
750.75
Formula:
C37H42N4O13
Chemical Name:
N’-[(1E)-1-[(2S,4S)-4-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl]-2-hydroxyethylidene]-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanehydrazide
Smiles :
C[C@@H]1O[C@H](C[C@H](N)[C@@H]1O)O[C@H]1C[C@@](O)(CC2C1=C(O)C1C(=O)C3=C(C=CC=C3C(=O)C=1C=2O)OC)/C(/CO)=N/NC(=O)CCCCCN1C(=O)C=CC1=O
InChiKey:
OBMJQRLIQQTJLR-USGQOSEYSA-N
InChi :
InChI=1S/C37H42N4O13/c1-17-32(46)20(38)13-27(53-17)54-22-15-37(51,23(16-42)39-40-24(43)9-4-3-5-12-41-25(44)10-11-26(41)45)14-19-29(22)36(50)31-30(34(19)48)33(47)18-7-6-8-21(52-2)28(18)35(31)49/h6-8,10-11,17,20,22,27,32,42,46,48,50-51H,3-5,9,12-16,38H2,1-2H3,(H,40,43)/b39-23+/t17-,20-,22-,27-,32+,37-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Fenebrutinib} web|{Fenebrutinib} Protein Tyrosine Kinase/RTK|{Fenebrutinib} Technical Information|{Fenebrutinib} Purity|{Fenebrutinib} manufacturer|{Fenebrutinib} Autophagy}
Shelf Life:
≥360 days if stored properly.{{Clioquinol} MedChemExpress|{Clioquinol} Parasite|{Clioquinol} Biological Activity|{Clioquinol} In Vivo|{Clioquinol} custom synthesis|{Clioquinol} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Aldoxorubicin, also known as INNO-206 and Doxorubicin-EMCH, is a prodrug of the anthracycline antibiotic doxorubicin.PMID:23962101 Aldoxorubicin binds selectively to the cysteine-34 position of albumin via its maleimide moiety, inhibiting DNA synthesis and inducing apoptosis.|Product information|CAS Number: 1361644-26-9|Molecular Weight: 750.75|Formula: C37H42N4O13|Chemical Name: N’-[(1E)-1-[(2S,4S)-4-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl]-2-hydroxyethylidene]-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanehydrazide|Smiles: C[C@@H]1O[C@H](C[C@H](N)[C@@H]1O)O[C@H]1C[C@@](O)(CC2C1=C(O)C1C(=O)C3=C(C=CC=C3C(=O)C=1C=2O)OC)/C(/CO)=N/NC(=O)CCCCCN1C(=O)C=CC1=O|InChiKey: OBMJQRLIQQTJLR-USGQOSEYSA-N|InChi: InChI=1S/C37H42N4O13/c1-17-32(46)20(38)13-27(53-17)54-22-15-37(51,23(16-42)39-40-24(43)9-4-3-5-12-41-25(44)10-11-26(41)45)14-19-29(22)36(50)31-30(34(19)48)33(47)18-7-6-8-21(52-2)28(18)35(31)49/h6-8,10-11,17,20,22,27,32,42,46,48,50-51H,3-5,9,12-16,38H2,1-2H3,(H,40,43)/b39-23+/t17-,20-,22-,27-,32+,37-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
