Product Name: GNB1L Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: ALEXA FLUOR® 350
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human GNB1L
Clonality: Polyclonal
CAS NO: 155521-46-3
Product: Pimelic Diphenylamide 106
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: DGCRK3; ESTM55; fb98e06; fj09d12; FKSG1; G-protein beta subunit-like protein; guanine nucleotide binding protein G protein, beta polypeptide 1-like; guanine nucleotide binding protein beta-subunit-like polypeptide; GY2; KIAA1645; WDR14; WDVCF; wu:fb98e06; wu:fj09d12; zgc:55774.
Background: This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders. Transcripts from this gene share exons with some transcripts from the C22orf29 gene. [provided by RefSeq, Jul 2008].
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27713163?dopt=Abstract
