Product Name: GNRPX Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: ALEXA FLUOR® 350
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human GNRPX/PLEKHJ1
Clonality: Polyclonal
CAS NO: 1370256-78-2
Product: Noscapine
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: Guanine nucleotide releasing protein x; Guanine nucleotide-releasing protein x; Likely ortholog of mouse guanine nucleotide releasing protein x; PH domain containing family J member 1; PH domain-containing family J member 1; PKHJ1_HUMAN; Pleckstrin homology domain containing family J member 1; Pleckstrin homology domain-containing family J member 1; PLEKHJ 1; PLEKHJ1; 9530063M10Rik; FLJ10297.
Background: PLEKHJ1 is a 149 amino acid phosphoprotein that contains one PH (pleckstrin homology) domain and is expressed in testis and liver. The gene that encodes PLEKHJ1 maps to human chromosome 19, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 contains the greatest gene density of the human chromosomes and is the genetic home for a number of immunoglobulin superfamily members, including killer cell and leukocyte Ig-like receptors, ICAMs, the CEACAM and PSG families, and Fc?receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes are also linked to chromosome 19.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25232658?dopt=Abstract
