Product Name: GPR 151 Polyclonal Antibody, Biotin Conjugated
Applications: WB, IHC-P
Reactivity: Human, Mouse, Rat
Conjugation: Biotin
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human GPR 151
Clonality: Polyclonal
CAS NO: 130308-48-4
Product: Pargyline (hydrochloride)
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: G protein coupled receptor 151; G protein coupled receptor PGR7; G-protein coupled receptor PGR7; Galanin receptor 4; Galanin receptor like; GALR4; GALRL; GP151_HUMAN; GPCR; GPCR-2037; GPCR2037; GPR 151; GPR151; PGR7; Probable G protein coupled receptor 151; Probable G-protein coupled receptor 151; Putative G protein coupled receptor; GPCR GPR151.
Background: GPCR2037 is a G protein-coupled receptor that undergoes weak activation by Galanin and is most abundant in the central nervous system (CNS), where it appears to be critical for development. During embryonal development the expression of GPCR2037 is widespread in the nervous system (dorsal thalamus, striatum, locus coeruleus and hindbrain nuclei). GPCR2037 in the CNS of 7- and 15-day-old mouse embryos can localize to the habenular complex. Low levels of GPCR2037 are detectable in testis, liver, kidney and stomach. In addition to GPCR2037, Galanin mediates its effects through receptor subtypes GALR1, 2 and 3. Galanin ligand exerts anxiolytic actions via GALR receptors under conditions of high stress. Galanin coexists with norepinephrine and serotonin in neural systems that mediate emotion.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19332149?dopt=Abstract
