Product Name: Histone H2A Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: ALEXA FLUOR® 594
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human Histone H2A
Clonality: Polyclonal
CAS NO: 55721-11-4
Squalamine
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: H2A; H2A/q; H2AFQ; H2A-GL101; Histone H2A type 2-C; Histone H2A-GL101; Histone H2A/q; HIST2H2AC
Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19755931?dopt=Abstract
